After Death, Twins’ Brains Reveal Similar Damage, University of Southern California Study

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Despite widespread use of a single term, Alzheimer’s disease is actually a diverse collection of diseases, symptoms, and pathological changes. What’s happening in the brain often varies widely from patient to patient, and a trigger for one person may be harmless is another. Researchers compared the brains of twins where one or both died of Alzheimer’s disease. They found that many of the twin pairs not only had similar progressions of Alzheimer’s disease and dementia prior to death, but they also had similar combinations of pathologies—two-or-more unconnected areas of damage to the brain.

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