CAMBRIDGE, Mass., Oct. 23 /PRNewswire-FirstCall/ -- Advanced Magnetics today announced that the independent Data Monitoring Committee (DMC) providing oversight of the ferumoxytol Phase III intravenous iron replacement therapy program met and informed the company that it has carefully reviewed the cumulative safety data from the ferumoxytol Phase III studies and identified no safety concerns. The DMC also recommended the continuation of the ferumoxytol Phase III studies with no modifications. At this meeting, the DMC reviewed safety data from over 1,200 subjects enrolled in the Phase III program.
Ferumoxytol, the key product in the company's development pipeline, is in Phase III multi-center clinical trials for use as an intravenous iron replacement therapeutic in chronic kidney disease patients, whether or not on dialysis.
The DMC has also met to review cumulative safety data in October 2005, February 2006 and June 2006. At each of these meetings, the DMC identified no safety concerns and recommended the continuation of the Phase III studies with no modifications. At all meetings, the DMC has available to it data on adverse events, serious adverse events and patient disposition.
About Advanced Magnetics
Advanced Magnetics, Inc. is a developer of superparamagnetic iron oxide nanoparticles used in pharmaceutical products. As a leader in our field, we are dedicated to the development and commercialization of our proprietary nanoparticle technology for use in therapeutic iron compounds to treat anemia, as well as novel imaging agents to aid in the diagnosis of cancer and cardiovascular disease. For more information about us, please visit our website at http://www.advancedmagnetics.com, the content of which is not part of this press release.
Contact: Lisa Gordon, VP of Business Development and Strategy Advanced Magnetics, Inc. (617) 498-3321 lgordon@advancedmagnetics.com
Advanced Magnetics, Inc.CONTACT: Lisa Gordon, VP of Business Development and Strategy for AdvancedMagnetics, Inc., +1-617-498-3321, lgordon@advancedmagnetics.com
Web site: http://www.advancedmagnetics.com/
