WATERTOWN, Mass.--(BUSINESS WIRE)--Acusphere, Inc. (NASDAQ: ACUS) announced today that on August 12, 2008, the company received a letter from NASDAQ indicating that based on the company’s stockholders’ equity as reported in its Quarterly Report on Form 10-Q for the quarter ended June 30, 2008, Acusphere does not comply with the minimum stockholders’ equity requirement of $10 million for continued listing on The NASDAQ Global Market as set forth in NASDAQ Marketplace Rule 4450(a)(3).