MedPageToday -- Statins are not only safe and effective for patients with liver enzyme abnormalities but also appear to improve their liver function, researchers found. Statins are not only safe and effective for patients with liver enzyme abnormalities but also appear to improve their liver function, researchers found. Liver test results in patients with moderately abnormal liver tests at baseline -- possibly associated with non-alcoholic fatty liver disease -- improved with statin treatment but continued to worsen on usual care without statin treatment (P<0.0001), Dimitri P. Mikhailidis, MD, of University College London, and colleagues reported online in The Lancet.