Vical Incorporated Announces Webcast Of CEO Presentation At Rodman & Renshaw Techvest Conference

SAN DIEGO, Oct. 31 /PRNewswire-FirstCall/ -- Vical Incorporated today announced that its presentation at the Rodman & Renshaw Techvest 7th Annual Healthcare Conference will be webcast live on Tuesday, November 8, 2005, at 4:55 p.m. Eastern Time. Vical’s President and Chief Executive Officer, Vijay B. Samant, will provide an overview of the company’s technologies, development programs, and strategic partnerships. The audio webcast and slides will be available through a link in the Webcast Center at www.vical.com. A replay will be available.

About Vical

Vical researches and develops biopharmaceutical products based on its patented DNA delivery technologies for the prevention and treatment of serious or life-threatening diseases. Potential applications of the company’s DNA delivery technology include DNA vaccines for infectious diseases or cancer, in which the expressed protein is an immunogen; cancer immunotherapeutics, in which the expressed protein is an immune system stimulant; and cardiovascular therapies, in which the expressed protein is an angiogenic growth factor. The company has retained all rights to its internally developed product candidates. In addition, the company collaborates with major pharmaceutical companies and biotechnology companies that give it access to complementary technologies or greater resources. These strategic partnerships provide the company with mutually beneficial opportunities to expand its product pipeline and serve significant unmet medical needs. Additional information on Vical is available at www.vical.com.

This press release contains forward-looking statements subject to risks and uncertainties that could cause actual results to differ materially from those projected, including: whether any product candidates will be shown to be safe and efficacious in clinical trials, the timing of clinical trials, whether Vical or its collaborative partners will seek or gain approval to market any product candidates, the dependence of the company on its collaborative partners, and additional risks set forth in the company’s filings with the Securities and Exchange Commission. These forward-looking statements represent the company’s judgment as of the date of this release. The company disclaims, however, any intent or obligation to update these forward-looking statements.

Contacts: Investors: Media: Alan R. Engbring Susan Neath Vical Incorporated Atkins + Associates (858) 646-1127 (858) 527-3486 Website: www.vical.com

Vical Incorporated

CONTACT: Investors, Alan R. Engbring of Vical Incorporated,+1-858-646-1127; or Media, Susan Neath of Atkins + Associates,+1-858-527-3486, for Vical Incorporated

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