Researchers have uncovered new details about the genetic underpinnings of cells known as Tregs, which are currently being tested as treatments for diseases such as type I diabetes, arthritis and lupus. Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body’s own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease.