Although a glass of wine a day may be good for your heart, drinking much more than this seems to promote “plaque” build-up in blood vessels, suggest the findings from a study of older adults. According to Dr. Kenneth J. Mukamal and colleagues, the few studies that have directly analyzed the relationship between alcohol use and arterial plaque, or atherosclerosis, have yielded inconsistent results, and none specifically looked at the risk in elderly individuals.