July 1, 2011 Bar Harbor, Maine — A National Institutes of Health grant of $2,282,840 awarded to Jackson Laboratory researchers will support the expansion of a database vital to scientists studying normal infant development and the errors in gene expression that lead to birth defects, cancer and other diseases.
The Gene Expression Database (GXD) for Mouse Development allows researchers worldwide to examine patterns of gene expression in the mouse, the most important experimental model for humans, in order to better understand biologically important molecular networks and to explore the genetic programs that underlie normal development and disease.
Jackson Associate Professor Martin Ringwald, Ph.D., who directs GXD, explains, "Gene expression data can provide researchers with critical insights into the function of genes and the molecular mechanisms of development, differentiation and disease. By combining different types of expression data and adding new data on a daily basis, GXD provides increasingly complete information about expression profiles of transcripts and proteins in mice."
The award, representing the first year of a five-year grant, was issued by the Eunice Kennedy Shriver National Institute of Child Health & Human Development, one of the National Institutes of Health.
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