Synta Pharmaceuticals and University of Toronto Researchers Elucidate Elesclomol Mechanism of Action Using Innovative Yeast-based Technology

LEXINGTON, Mass.--(BUSINESS WIRE)--Synta Pharmaceuticals Corp. (NASDAQ: SNTA) – A report published in the peer-reviewed journal PLoS ONE demonstrate how a novel yeast screening platform pioneered by researchers at the University of Toronto was used to elucidate the mechanism of action of elesclomol, a first-in-class drug that targets cancer cell metabolism and is currently being clinically developed by Synta Pharmaceuticals Corp. of Lexington, Massachusetts. Elesclomol is currently in clinical trials in both solid tumor and hematologic cancers, including a study in combination with paclitaxel in ovarian cancer and a single agent study in acute myeloid leukemia (AML) currently being conducted at Princess Margaret Hospital in Toronto.
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