Study Shows Rapamycin Reverses Myocardial Defects in Mouse Model of LEOPARD Syndrome, Beth Israel Deaconess Medical Center Reveals

Physorg.com -- Congenital heart diseases affect approximately one in 100 patients, making them the most common type of birth defect and the number-one cause of pediatric deaths. Now a new study showing that the mTOR inhibitor drug rapamycin can reverse cardiac muscle damage in a mouse model of the congenital disease LEOPARD syndrome not only identifies the first possible medical treatment for this rare condition, but also demonstrates the importance of targeted therapies in managing congenital diseases.

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