Seegene, Inc. and DuPont Nutrition & Health Agree to Develop Highly Multiplexed Molecular Assays for Food Safety Testing

WILMINGTON, DE and SEOUL, SOUTH KOREA--(Marketwire - May 24, 2012) - Seegene Inc. (KOSDAQ: 096530), a leading developer of multiplex molecular technologies and diagnostic tests, and DuPont Nutrition & Health, a leading provider of rapid, molecular diagnostic systems, have agreed to jointly develop new, highly multiplexed assays for the detection of foodborne pathogens.

Combining novel technologies from Seegene with the powerful chemistry and analytics of the BAX® System from DuPont allows for a potential step-change in pathogen testing. For example, Seegene DPO™ technology generates consistently high specificity by eliminating primer competition, and TOCE™ technology allows the identification of multiple targets in a single dye channel. With this agreement, DuPont and Seegene are seeking to develop highly multiplexed, real-time PCR assays that provide for rapid detection and differentiation of 10 or more organisms from a single sample in a single test.

“We are constantly seeking innovative collaborators to develop science-based solutions that will meet evolving needs for food safety and quality,” said George Tice, research and development director, DuPont Qualicon Diagnostics. “This integration of unique Seegene technologies with robust diagnostic systems from DuPont will give the food industry increasingly powerful tools to help protect their products and their brands.”

“Working with DuPont Qualicon Diagnostics opens a significant new market opportunity for our portfolio of multiplex molecular technologies,” said Jong-Yoon Chun, founder and CEO of Seegene. “By leveraging these novel technologies, we can advance from the current ‘one test, one pathogen’ approach to a ‘one test, many pathogens’ paradigm. This will significantly improve the efficiency and effectiveness of food safety testing, and help to reduce the prevalence of foodborne illness.”

This initiative marks the entry of Seegene’s multiplex technologies into the multi-billion dollar food safety testing market. According to The Centers for Disease Control and Prevention, foodborne illness each year in the United States alone affects 48 million people.

DPO™ technology is a fundamental tool for blocking extension of non-specifically primed templates, generating assays that are both highly specific and highly sensitive. TOCE enables simultaneous multiplex testing, by using the differences in melting temperatures of designed artificial amplicons. Prior to TOCE, multiplex assays were difficult because even a small variation in amplicon sequences changes the melting temperature (Tm) of the amplicon. TOCE technology overcomes current limitations of Tm analysis and allows testing of multiple targets with one fluorescent label by ensuring that sequence variation does not change the melting temperature.

Food processing companies around the world rely on the BAX® system from DuPont Qualicon Diagnostics to detect pathogens or other organisms in raw ingredients, finished products and environmental samples. The automated system uses leading-edge technology, including polymerase chain reaction (PCR) assays, tableted reagents and optimized media to detect Salmonella, Listeria species, Listeria monocytogenes, E. coli O157:H7 and STEC, Cronobacter, Campylobacter, Staphylococcus aureus, Vibrio, and yeast and mold. With certifications and regulatory approvals in the Americas, Asia and Europe, the BAX® system is one of the most advanced pathogen testing system available to food companies. For more information, please visit www.qualicon.com

Seegene is the world’s leading developer of multiplex molecular technologies and multiplex clinical molecular diagnostics (M-MoDx). Seegene’s core enabling technologies -- ACP™, DPO™, READ, and TOCE™ -- are the foundation for M-MoDx tests that can simultaneously detect multiple targets with high sensitivity, specificity and reproducibility. Seegene’s products detect multi-pathogens with great reliability and throughput, ultimately providing the most economical basis for saving time, labor and cost. Seegene’s mission is to maintain leadership in molecular diagnostics for infectious diseases, genetics, pharmacogenetics, and oncology using innovative proprietary technologies. For more information please visit www.seegene.com or call +301-762-9066.

The DuPont Nutrition & Health division addresses the world’s challenges in food by offering a wide range of sustainable, bio-based ingredients and advanced microbial diagnostic solutions to provide safer, healthier and more nutritious food. Through close collaboration with customers, DuPont combines knowledge and experience with a passion for innovation to deliver unparalleled customer value to the marketplace.

DuPont (NYSE: DD) has been bringing world-class science and engineering to the global marketplace in the form of innovative products, materials, and services since 1802. The company believes that by collaborating with customers, governments, NGOs, and thought leaders we can help find solutions to such global challenges as providing enough healthy food for people everywhere, decreasing dependence on fossil fuels, and protecting life and the environment. For additional information about DuPont and its commitment to inclusive innovation, please visit http://www.dupont.com and http://www.qualicon.com.

Photos available at http://www2.dupont.com/Qualicon/en_US/about_dq/dq_photo_gallery.html

The DuPont Oval Logo, DuPont™, The miracles of science™ and BAX® are registered trademarks, trademarks of DuPont or its affiliates.
BAX® is a registered trademark of DuPont for its line of equipment, reagents and software used to analyze samples for microbial contamination.
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