MALVERN, Pa.--(BUSINESS WIRE)--Promedior, Inc., a leader in the development of novel therapeutics for the treatment of fibrotic diseases and tissue remodeling, announced today the publication of results from preclinical studies demonstrating that human Serum Amyloid P (hSAP) potently inhibited fibrosis in two independent model systems of kidney fibrosis. The study results indicate a potential role for hSAP in treating kidney diseases such as diabetic nephropathy and transplant nephropathy where interstitial fibrosis plays a significant pathological role. The results are published in the November 4, 2009 issue of Science Translational Medicine, and confirm previously published data demonstrating the broad anti-fibrotic activity of SAP in models of pulmonary fibrosis and cardiac fibrosis.
