According to Towards Healthcare data, the plasmid purification market size is estimated at USD 1.95 billion in 2024, growing to USD 2.18 billion in 2025, and is projected to reach approximately USD 5.88 billion by 2034, rising at a CAGR of 11.64% from 2024 to 2034.
The plasmid purification market has experienced significant growth in recent years, driven by high demand for plasmids across various domains, including genetics, biotechnology, and the development of treatments. Technological advancements have further helped the growth of the plasmid purification market.
The Complete Study is Now Available for Immediate Access | Download the Sample Pages of this Report @ https://www.towardshealthcare.com/download-sample/5485
Key Highlights of Plasmid Purification Market
➢ By region, North America dominated the plasmid purification market share by 41% in 2024, whereas the Asia Pacific is expected to grow in the foreseeable period.
➢ By product and service, the products segment led the plasmid purification market in 2024, whereas the services segment is expected to grow in the forecast period.
➢ By grade, the molecular grade segment led the plasmid purification market in 2024, whereas the transfection-grade segment is expected to grow in the expected timeframe.
➢ By application, the protein and cloning segment led the plasmid purification market in 2024, whereas the transfection and gene editing segment is expected to grow in the foreseeable period.
➢ By end-use, the academic and research institutes led the plasmid purification market in 2024, whereas the contract research organizations are expected to grow with the highest CAGR in the foreseen period.
Market Overview
The process of separating plasmid DNA from ribosomes, genomic DNA, bacterial cell wall, and proteins is known as plasmid purification. Use of plasmid DNA (pDNA) for gene therapy and vaccines, along with non-viral vectors, has helped the growth of the market. Technological advancement, helping with gene purification with the help of AI and ML, has also helped the development of the plasmid purification market rapidly in recent years. Producing recombinant proteins essential for the biotechnology and pharmaceutical sectors also relies on plasmid isolation, which further supports the market's growth. The procedure is also necessary as it is helpful for the production of medicinal proteins, vaccines, and enzymes.
New Trends in the Plasmid Purification Market
➢ Adoption of automation by the plasmid purification market is aiding its growth as the advanced technology helps in speeding up the process, along with enhancing the efficiency, consistency, and improving large-scale production.
➢ Technologically advanced plasmid-purification methods, such as multicolumn continuous chromatography, are also aiding the market’s growth, along with benefits such as higher yields and reduced contamination.
➢ Pharmaceutical companies are not outsourcing the plasmid production and purification process to CDMOs for a timely procedure, further enhancing the market’s growth.
You can place an order or ask any questions, please feel free to contact us at sales@towardshealthcare.com
What is the Role of AI in the growth of the Plasmid Purification Market?
Plasmids are manufactured on a large scale and have high demand in various domains, including genetics, biotechnology, and the development of multiple therapies. Technologically advanced methods in the form of AI and ML are also helping the growth of the market. The automation procedure performed under AI's guidance is helping to accelerate and improve the plasmid production and purification method, further aiding the market’s growth. AI also helps to lower the price and maintain efficiency and production quantity, along with maintaining stability, which is one of the important factors for the growth of the market. AI also helps in personalized treatment options for better therapy and effective results.
Market Dynamics
Driver
Advanced Technology helping the Growth of the Market
Use of technologically advanced methods for plasmid production and purification is one of the major factors for the growth of the plasmid purification market. The automation technology helps to speed up the purification process while maintaining efficiency and stability, thereby yielding better results and further aiding the growth of the plasmid purification market. Affinity chromatography enables researchers to achieve better yields and higher purity levels, thereby further enhancing the market's growth. Enhancing proteomics and genomic research are also some of the major factors for the development of the market.
Challenge
High Costs of Plasmid Purification are restraining the Growth of the Market
The high costs of plasmid purification methods and the apparatus used for this purpose are one of the major factors restraining the growth of the plasmid purification market. Research organizations of underdeveloped nations may not be able to afford such technologically advanced methods, which is another major factor obstructing the market’s growth. Use of specialized equipment like HPLC systems, costly reagents, and purification kits involves major costs, restraining the growth of the market.
Get the latest insights on life science industry segmentation with our Annual Membership: https://www.towardshealthcare.com/get-an-annual-membership
Opportunity
High Gene Therapy Demand Enhancing Market’s Growth
Growing applications of gene therapy are helping the growth of the market in the recent periods. The requirement of high-quality pDNA necessary for the introduction of therapeutic genetic information into cells is another major factor helpful for the growth of the plasmid purification market. It also helps to cure various unknown illnesses and hereditary abnormalities, further enhancing the market’s growth. Developments of bioprocessing technology and regulatory frameworks to meet a certain medical range are also helpful for the market’s growth in the foreseeable period.
Regional Insights
|
Region |
2024 Market Share (%) |
|
North America |
41% |
|
Europe |
29% |
|
Asia Pacific |
25% |
|
Latin America |
3% |
|
Middle East and Africa |
2% |
North America led the Plasmid Purification Market in 2024
North America dominated the plasmid purification market share by 41% in 2024, driven by significant investments in the development of novel biopharmaceutical medications in the region. The US and Canada contribute on a higher scale in the growth of the market in the area by having the most copyrights of intellectual properties of newly created therapies. The rising demand for gene and cell therapies, combined with technologically advanced methods and enhanced healthcare facilities in the region, is also a major factor driving the growth of the plasmid purification market.
Download the single region market report @ https://www.towardshealthcare.com/price/5485
Asia Pacific is expected to grow in the forecast period.
Asia Pacific is observed to be the fastest-growing region in the foreseen period, aiding the growth of the plasmid purification market. High investment in pharmaceutical industries, research and development, and biotechnology has also contributed to the market's growth in the region. Countries like India, China, Japan, and South Korea have made significant contributions to the development of the plasmid purification market in the Asia Pacific, driven by their advancements in genetic medicine capabilities and efforts to promote innovation in bioprocessing technologies, which are essential for plasmid DNA production.
Segmental Analysis
By Product and Service
The products segment led the plasmid purification market in 2024 due to high demand for plasmid purification kits, which include specific buffers and columns to separate high-quality DNA, further fueling the market’s growth. Researchers highly utilize such kits to purify plasmids, and hence, they are essential for the growth of the market. Multiple methods, depending upon the requirement, scientists prefer the plasmid isolation method, which is also cost-effective, further fuelling the growth of the market.
The services segment is expected to grow in the foreseen period due to technological advancements and automation in the plasmid isolation and purification process for faster results with maintained efficiency. Plasmid purification services also offer specialized pDNA extraction and purification from bacterial cells, producing high-quality samples, which further enhances the growth of the plasmid purification market in the foreseeable future. The segment also observes growth due to its demand in cloning, sequencing, and transfection.
Become a valued research partner with us - https://www.towardshealthcare.com/schedule-meeting
By Grade
The molecular grade segment dominated the plasmid purification market in 2024, as it allows scientists to choose from a variety of methods of plasmid isolation depending on the requirement. The segment also experiences significant growth, as it is cost-effective, provides quicker results, and is ideal for situations where high-purity levels are not required, such as in cloning, nucleic acid labeling, PCR, and sequencing.
The transfection-grade segment is observed to grow with the highest CAGR in the forecast period, aiding the plasmid purification market. The segment is highly essential for applications requiring higher purity and yields. The segment is also beneficial and recommended for the transfection of delicate cell lines or for in vivo studies. Utmost purity is ensured in the transfection-grade method, which is essential for multiple applications, further enhancing the growth of the plasmid purification market.
By Application
The cloning and protein expression segment led the plasmid purification market in 2024. Researchers use cloning and gene expression for a variety of purposes, such as understanding biological issues, gene functions, analysing molecular pathways, studying disease, developing embryos, and various other methods, further fuelling the growth of the market. Researchers then choose the best cloning technique and protein expression method as per the gene sequencing for the growth of the market.
The transfection and gene editing segment is expected to grow in the foreseen period, aiding the growth of the plasmid purification market. Transfection is a method of introducing nucleic acids into eukaryotic cells. The cells can be transfected either transiently for short-term protein expression or permanently for DNA incorporation into the genome. Transfecting cells through various means enables researchers to study the function of genes and their expression in a cellular context.
By End Use
The academic and research institutes segment led the plasmid purification market in 2024. Basic and applied molecular biology research encompassing a wide range of species from eubacteria to humans has been transformed by the advent of gene technology techniques. Plasmids are also essential for various activities, including fundamental molecular and structural biology research, genetic engineering research, gene therapy, and similar purposes, thereby contributing to market growth.
The contract research organizations segment is expected to grow within the scheduled timeframe, further fueling the market's growth. Such organizations provide essential services such as drug development, clinical trials, and genetic testing, which are helpful for the growth of the plasmid purification market.
Browse More Insights of Towards Healthcare:
The global viral vector and plasmid DNA manufacturing market was valued at US$ 6.01 billion in 2023 and is projected to surge to US$ 43.04 billion by 2034, expanding at a CAGR of 20.7% from 2024 to 2034.
The U.S. viral vector and plasmid DNA manufacturing market was valued at US$ 2.85 billion in 2024, expected to reach US$ 3.3 billion in 2025, and is anticipated to hit US$ 12.31 billion by 2034, progressing at a CAGR of 15.72% between 2025 and 2034.
The Asia-Pacific (APAC) viral vector and plasmid DNA manufacturing market stood at US$ 1.38 billion in 2024, grew to US$ 1.68 billion in 2025, and is forecasted to attain US$ 10.01 billion by 2034, registering a CAGR of 21.93% over the same period.
The global plasmid DNA manufacturing market was valued at US$ 1.85 billion in 2023 and is expected to climb to US$ 12.27 billion by 2034, reflecting a CAGR of 18.77% from 2024 to 2034.
Within this segment, the global GMP plasmid DNA manufacturing market was valued at US$ 250 million in 2024, grew to US$ 273.35 million in 2025, and is projected to reach US$ 608.57 million by 2034, advancing at a CAGR of 9.34% between 2025 and 2034.
The global plasma-derived medicine market stood at US$ 15.96 billion in 2023 and is predicted to rise to US$ 37.4 billion by 2034, expanding at a CAGR of 8.05% during the forecast period.
Similarly, the blood plasma fractionation market was valued at US$ 30.93 billion in 2023 and is projected to reach US$ 74.74 billion by 2034, registering a CAGR of 8.35% from 2024 to 2034.
The plasma protein products market was valued at US$ 32.8 billion in 2023 and is anticipated to grow to US$ 72.9 billion by 2034, progressing at a CAGR of 7.53% from 2024 to 2034.
Meanwhile, the global blood bank and plasma freezer market stood at US$ 95 million in 2023 and is forecasted to reach US$ 168.36 million by 2034, growing at a CAGR of 5.34% over the same period.
Additionally, the global specialty control plasma market was valued at US$ 10.42 billion in 2024, increased to US$ 11.09 billion in 2025, and is expected to attain US$ 19.42 billion by 2034, expanding at a CAGR of 6.44% between 2025 and 2034.
Recent Developments in the Plasmid Purification Market
➢ In May 2025, Thermo Fisher Scientific introduced its Applied Biosystems MagMAX Pro HT NoSpin Plasmid MiniPrep Kit for the high demand of rapid and automated DNA isolation for scientists to perform quick and affordable experiments.
➢ In May 2025, CDMO 3PBIOVIAN launched the AAVion platform, a fully integrated adeno-associated virus (AAV) manufacturing solution for gene therapy development.
Top Companies of the Plasmid Purification Market
• Merck KGaA
• QIAGEN
• Thermo Fisher Scientific, Inc.
• Takara Bio
• Promega Corporation
• Zymo Research
• MP BIOMEDICALS
• New England Biolabs
• MCLAB
• Applied Biological Materials Inc.
Download the Competitive Landscape market report @ https://www.towardshealthcare.com/price/5485
Segments Covered in the Report
By Product & Service
• Products
• Instruments
• Kits & Reagents
• Services
By Grade
• Molecular Grade
• Transfection Grade
By Application
• Cloning & Protein Expression
• Transfection & Gene Editing
• Others
By End-use
• Academic & Research Institutes
• Contract Research Organizations
• Pharmaceutical & Biotechnology Companies
By Region
North America
• U.S.
• Canada
Asia Pacific
• China
• Japan
• India
• South Korea
• Thailand
Europe
• Germany
• UK
• France
• Italy
• Spain
• Sweden
• Denmark
• Norway
Latin America
• Brazil
• Mexico
• Argentina
Middle East and Africa (MEA)
• South Africa
• UAE
• Saudi Arabia
• Kuwait
Immediate Delivery Available | Buy This Premium Research @ https://www.towardshealthcare.com/price/5485
Access our exclusive, data-rich dashboard dedicated to the healthcare market - built specifically for decision-makers, strategists, and industry leaders. The dashboard features comprehensive statistical data, segment-wise market breakdowns, regional performance shares, detailed company profiles, annual updates, and much more. From market sizing to competitive intelligence, this powerful tool is one-stop solution to your gateway.
Access the Dashboard: https://www.towardshealthcare.com/access-dashboard
About Us
Towards Healthcare is a leading global provider of technological solutions, clinical research services, and advanced analytics, with a strong emphasis on life science research. Dedicated to advancing innovation in the life sciences sector, we build strategic partnerships that generate actionable insights and transformative breakthroughs. As a global strategy consulting firm, we empower life science leaders to gain a competitive edge, drive research excellence, and accelerate sustainable growth.
You can place an order or ask any questions, please feel free to contact us at sales@towardshealthcare.com
Europe Region: +44 778 256 0738
North America Region: +1 8044 4193 44
APAC Region: +91 9356 9282 04
Web: https://www.towardshealthcare.com
Our Trusted Data Partners
Precedence Research | Statifacts | Towards Packaging | Towards Automotive | Towards Food and Beverages | Towards Chemical and Materials | Towards Consumer Goods | Towards Dental | Towards EV Solutions | Nova One Advisor | Healthcare Webwire | Packaging Webwire | Automotive Webwire
Find us on social platforms: LinkedIn | Twitter | Instagram | Medium | Pinterest
