Penwest Pharmaceutical To Present At SG Cowen & Co., LLC Global Healthcare Conference

DANBURY, Conn., Nov. 4 /PRNewswire-FirstCall/ -- Penwest Pharmaceuticals Co. today announced that Jennifer Good, Senior Vice President, Finance, and Chief Financial Officer of Penwest, and Dr. Thomas Sciascia, M.D., Senior Vice President and Chief Medical Officer, are scheduled to discuss the Company at the 6th Annual SG Cowen & Co. Global Healthcare Conference. The conference is being held on November 9 and 10, 2005, at the Hilton Diagonal Mar in Barcelona, Spain.

Ms. Good and Dr. Sciascia are scheduled to present on Thursday, November 10 at 3:10 p.m. local time (9:10 a.m. Eastern time).

The live audio webcast of Penwest’s presentation can be accessed at http://www.corporate-ir.net/ireye/confLobby.zhtml?ticker=PPCO&item_id=11 52257. A replay of the webcast will be available approximately one hour after the completion of the presentation and will be accessible for 90 days.

Penwest Pharmaceuticals

Penwest develops pharmaceutical products based on innovative oral drug delivery technologies. We are focusing our development efforts principally on products that address diseases of the central nervous system. The foundation of our technology platform is TIMERx(R), an extended release delivery system that is adaptable to soluble and insoluble drugs and that is flexible for a variety of controlled release profiles. We have also developed two additional oral drug delivery systems, Geminex(R) and SyncroDose(TM). Geminex is a dual drug delivery system that is designed to provide independent release of different active ingredients contained in a drug, and SyncroDose is a drug delivery system that is designed to release the active ingredient of a drug at the desired site and time in the digestive tract.

Contact: Jennifer Good Caroline Gentile/Jim Fingeroth Senior Vice President and Kekst and Company Chief Financial Officer (212) 521-4800 (203) 796-3701 (877) 736-9378

Penwest Pharmaceuticals Co.

CONTACT: Jennifer Good Senior Vice President and Chief Financial Officerof Penwest Pharmaceuticals Co., +1-203-796-3701, or 1-877-736-9378;Caroline Gentile/Jim Fingeroth, both of Kekst and Company, +1-212-521-4800

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