LEWISVILLE, Texas--(BUSINESS WIRE)--Orthofix International N.V. (NASDAQ:OFIX) (the Company) today announced that its sports medicine division, Breg®, has signed a contract with Novation to be the exclusive manufacturer of cold therapy products for NOVAPLUS®, the private label brand of Novation. With over 35,000 members, Novation is the largest group purchasing organization in the United States. The contract was effective as of November 1, 2010.