MONTREAL, QUEBEC -- (MARKET WIRE) -- September 29, 2006 -- Mistral Pharma Inc.(TSX VENTURE: MIP) (“Mistral”) announces today that the board of directors of Mistral has approved the grant of stock options to purchase an aggregate of 625,000 common shares of Mistral at an exercise price of $0.10 per share to certain directors of Mistral. This grant is made pursuant to the stock option plan of Mistral. These stock options will expire on September 29, 2011.