Millennium: The Takeda Oncology Company’s VELCADE(R) (Bortezomib) for Injection Based Combinations Deliver Two-Year Overall Survival Rates of Up to 88 Percent in Patients with Previously Untreated Multiple Myeloma

NEW ORLEANS--(BUSINESS WIRE)--Millennium: The Takeda Oncology Company today reported the presentation of results from a double randomized Phase III clinical trial of VELCADE based combinations for the treatment of patients with previously untreated multiple myeloma (MM). The VELCADE based combinations evaluated in the study demonstrated two-year overall survival rates ranging between 81 and 88 percent. The results showed a notable increase in the rate of complete remissions (CR), which nearly doubled from 23 percent after six cycles of induction to 42 percent after VELCADE based maintenance treatment. The rigor of double randomization isolates the impact of VELCADE based maintenance therapy, independent of the induction regimen. These cooperative group data were generated by the Spanish Myeloma Group PETHEMA/GEM and presented by Maria-Victoria Mateos, M.D., Ph.D., Hospital Universitario de Salamanca, Salamanca, Spain. This presentation was selected for the distinguished plenary session at the 51st Annual Meeting of the American Society of Hematology (ASH), held December 5-8, 2009 in New Orleans, Louisiana.
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