Metagenomics refers to the study of genomes collectively in a microbial community and it involves analyzing genomes without culturing organisms in the community.
Metagenomics refers to the study of genomes collectively in a microbial community and it involves analyzing genomes without culturing organisms in the community. The process of metagenomics is the key factor behind the developments in microbial evolution, ecology, and diversity. The applications of metagenomics sequencing in various fields, initiatives, and decline in the cost of sequencing have increased its demand.
According to Portland based research firm, Allied Market Research, the global metagenomic sequencing market is projected to garner $3.64 billion by 2028, growing at a CAGR of 17.5% from 2021 to 2028. Initiatives and funding from private and government bodies for large-scale sequencing projects, advancements in metagenomics sequencing, and the declining cost of sequencing have boosted the growth of the market.
“The overall impact of COVID-19 pandemic is likely to remain positive for the metagenomics sequencing market. As, throughout the COVID-19 pandemic, clinical diagnostics and testing is a critical component of the response and is on a rapid increase with the rise in number of cases, which enables rapid identification and isolation of infected individuals. The majority of this testing is PCR-based, detecting the presence of the SARS-CoV-2 virus; thereby, having a positive impact on the market”
For years, microbial genome sequencing was restricted to a small number of species that can be grown in pure culture. Over the last two decades, new methods came into the light that allowed researchers to develop culture-independent methods directly from the environmental samples. However, the latest developments enabled researchers to study gene pools and generate accurate DNA sequences.
Metagenomics for DNA sequencing
Metagenomics involves sequencing DNA samples that are categorized as “tricky”. Such DNA shows high heterogeneity that can lead to interspecies misassemblies and could threaten the purpose of metagenomics sequencing. However, a group of scientists from Tokyo Tech has found a new metagenomics assembly, MetaPlatanus that can generate exact DNA sequences including the sequences of uncultured organisms. According to their research, MetaPlatanus uses short DNA sequence reads to assemble contigs, which are long stretches of DNA sequences that are similar to jigsaw puzzle pieces in the longer genome. Such contigs are assembles using various inputs such as long-range sequences links, coverage depths, and binning information into larger chromosome-scale scaffolds.
Explore In-depth market data- https://www.alliedmarketresearch.com/request-sample/5059
Metagenomics sequencing for enzyme bioprospecting
Microorganisms are present at every corner of the world and the majority of them are complicated to cultivate by traditional tools and techniques. The emergence of metagenomics sequencing has opened new opportunities in the field of microbial biotechnology and allowed the recovery of genetic material directly from the environment without cultivation techniques. In addition, the next generation of metagenomics sequencing techniques leads to the generation of large sequence data sets derived from several environments including the human body, soil, and ocean water.
Apart from this, metagenomics sequencing could be a key for treating infectious diseases including Covid-19. Theoretically, metagenomics next-generation sequencing (mNGS) has the potential to detect any microbe present in a host and infer characteristics of pathogen’s phenotypic. This would increase the demand for metagenomics sequencing techniques in the future and encourage the growth of the metagenomic sequencing market.