CAMBRIDGE, Mass — MIT researchers have found that the children of mothers whose water supplies were contaminated with arsenic during their pregnancies harbored gene expression changes that may lead to cancer and other diseases later in life. In addition to establishing the potential harmful effects of these prenatal exposures, the new study also provides a possible method for screening populations to detect signs of arsenic contamination.This is the first time evidence of such genome-wide changes resulting from prenatal exposure has ever been documented from any environmental contaminant. It suggests that even when water supplies are cleaned up and the children never experience any direct exposure to the pollutant, they may suffer lasting damage.
