The demand for nitric oxide gas has been increasing over the last few years due to its wide use in the healthcare sector.
The demand for nitric oxide gas has been increasing over the last few years due to its wide use in the healthcare sector. The nitric oxide gas is inhaled through the mouth or nose and is used to relax the smooth muscles and widen the blood vessels in the lungs. Mostly, inhaled nitric oxide is used with a breathing machine or ventilator to treat infants or newborn babies that suffer from respiratory failure caused by pulmonary hypertension.
Increase in the prevalence of respiratory treatment in neonates has resulted in increased use of inhaled nitric oxide therapy. Furthermore, increase in the prevalence of diseases in the newborn such as persistent pulmonary hypertension, and neonatal hypoxic respiratory failure (HRF) increased the demand for the growth of the inhaled nitric oxide market
According to Allied Market Research, the global inhaled nitric oxide market is expected to reach $1.18 billion by 2027, growing at a CAGR of 8.1% from 2020 to 2027. Rise in demand from the healthcare sector and surge in chronic diseases have boosted the market growth.
Use of inhaled nitric oxide in pediatric practice:
Nitric oxide gas plays a pivotal role in human physiology, especially in neural transmission and inflammation. Inhaled nitric oxide is a selective pulmonary vasodilator that has been widely used as a vital therapeutic agent, especially in pediatrics. The use of inhaled nitric oxide for hypoxaemic respiratory failure and treatment of postoperative pulmonary hypertension is widely accepted. However, there are some side effects to be considered before treatment, but so far, inhaled nitric oxide is the most suitable course to treatment in pulmonary hypertension in babies.
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Use of inhaled nitric oxide in cardiac surgery:
Over the last few years, the occurrence of right ventricular failure and pulmonary arterial hypertension has increased in children and adults. This postoperative complication can be treated with inhaled nitric oxide and is regarded as a major therapeutic advancement. Nitric oxide binds instantly with hemoglobin, which helps minimize post-operative complications. Moreover, it helps maintain systemic and coronary blood pressure. However, the amount of inhaled nitric oxide must be monitored as it could increase toxicity in the blood, especially in new-borns.
Apart from these, inhaled nitric oxide can be used in cardiothoracic surgeries. Pulmonary vascular resistance and hypoxemia can severely affect the management of cardiothoracic surgical patients. However, inhaled nitric oxide promises to be an effective therapy for cardiothoracic surgeons as it improves oxygenation and lowers pulmonary vascular resistance. The applications of inhaled nitric oxide have increased due to its ability to increase oxygenation in both adults and new-borns. As inhaled nitric oxide therapy is clinically approved, the opportunities in the industry would increase in the future.
Impact of Covid-19 on Inhaled Nitric Oxide Market (Pre and Post Analysis)
COVID-19 pandemic, Inhaled nitric oxide has antiviral properties and improved oxygenation. Therefore, nitric oxide is now being tested as an experimental treatment for COVID-19. It is also helpful in protecting healthcare workers on the front line of the pandemic from getting sick. Further, iNO is used for the treatment of pulmonary hypertension, ARDS, and other respiratory diseases, whereas several undergoing randomized clinical trials are being conducted to investigate the role of inhaled nitric oxide in COVID-19. Moreover, key players such as Mallinckrodt have also initiated a retrospective study for the use of iNO in COVID-19 patients. Moreover, multiple ongoing clinical trials are conducted for iNO as a treatment for COVID-19 and it is being used with promising results in the patient population.