Rising incidences of cancer, ongoing research on advanced cancer treatments, and growing application of T-Cell adoptive immunotherapy are some key factors expected to drive market growth.
Rising incidences of cancer, ongoing research on advanced cancer treatments, and growing application of T-Cell adoptive immunotherapy are some key factors expected to drive market growth
New York, December 16, 2021 – Reports and Data has published its latest report titled “T-Cell Therapy Market By Modality (Research, Commercialized), By Therapy, (CAR T-cell Therapy, T-cell Receptor (TCR)-based, Tumor Infiltrating Lymphocytes (TIL)-based), By Indication (Hematologic Malignancies, Solid Tumors), and By Region, Forecast to 2028”
According to the latest report by Reports and Data, the global T-cell therapy market size was USD 4.72 Billion in 2020 and is expected to reach USD 21 Billion in 2028 and register a revenue CAGR of 20.4% during the forecast period, 2021-2028.
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Drivers, Restraints, and Opportunities
T-cell therapy is a type of immunotherapy that is used to treat numerous types of cancers. The adaptive immune response relies heavily on white blood cells. White blood cells are taken from the patient's body and used in the cell reengineering procedure to change the structure of the cells. These T-cell receptors have been reengineered to recognize and destroy cancer cells on their surface. Hematologic malignancies and solid tumors are usually treated with these therapies, and increasing incidence of cancer has further boosted adoption of T-Cell therapies and is expected to drive market revenue growth over the forecast period.
Furthermore, growing awareness regarding advanced cancer treatments, development of healthcare infrastructure (especially during Covid 19 pandemic), and extensive research on CAR T-cell therapy and gene therapy techniques are other factors fuel revenue growth of the market. Chimeric Antigen Receptor T-cell therapy, popularly known as CAR T-cell therapy is regarded as effective methods of cancer treatment, especially in case of blood cancer. Tisagenlecleucel, Brexucabtagene autoleucel, Axicabtagene ciloleucel, Idecabtagene vicleucel, are some approved CAR T-cell therapies. However, high costs associated with CAR T-cell therapy and side effects of T-cell therapy such as neurologic difficulties, and cytokine release syndrome, are factors expected to restrain T-cell therapy market revenue growth during the forecast period.
COVID-19 Impact Analysis
- Social distancing and restrictions severely disrupted businesses and operations
- Lockdowns caused disruptions in transportation and logistics
- impacted manufacturing activities and mining operations globally
- Took a toll on economy of various countries
- Caused sudden and drastic downturn in economic activity
- Disrupted agriculture, fisheries, dairy, and other sectors
- Caused loss of employment and financial crisis
- Supply impacts were further compounded owing to reduced disposable income
- Emergence of variants continue to cause concerns and impact normal routines
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Hematologic Malignancies Segment to Lead in Terms of Revenue Share:
Hematologic malignancies segment is expected to account for largest revenue share in the global market over the forecast period attributed to high prevalence of leukemia worldwide, increasing government initiatives on the treatment of hematologic malignancies and growing use of T-cell therapy. Hematologic malignancies are cancers that affect the bone marrow, blood, lymph nodes or in the cells of the immune system.
CAR T-Cell Therapy Segment to Register Significant Revenue Growth:
CAR T-cell therapy segment is expected to register significant revenue growth over the forecast period due to rising number of clinical trials in the field of CAR T-cells and life sciences, growing need for cell-based therapy and increasing number of patients suffering from cancer. This therapy is also known as “living drug” as the cells can survive for a long time in the body, they can recognize and target cancer cells if and when a relapse occurs.
North America to Register Robust Revenue Growth Rate:
North America is expected to register robust revenue growth rate over the forecast period attributable to adoption of advanced technology in healthcare industry, increasing number of clinical trials of T-cell therapies, rising private investments on cancer-based research and development activities and presence of key players in the region.
Asia Pacific Accounted for Largest Revenue Share in 2020:
Asia Pacific is expected to account for largest revenue share in the global market in 2020 attributable to increasing government initiatives to accelerate advancements in healthcare sector and growing focus on cancer research owing to increasing incidences of cancer. In addition, increasing number of geriatric population suffering from cancer and increasing adoption of T-cell therapy as a cancer management strategy are some other key factors expected to drive revenue growth of the market.
Major Companies in the Market Include:
- Novartis AG
- Merck KGaA
- Gilead Sciences Inc.
- TCR2 Therapeutics Inc.
- Bluebird Bio Inc.
- Sorrento Therapeutics
- Fate Therapeutics
- Pfizer Inc.
- Amgen
- Celgene Corporation
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Market Segmentation:
For the purpose of this report, Reports and Data has segmented global T-cell therapy market based on modality, therapy, indication, and region:
Modality Outlook (Revenue, USD Billion; 2018-2028)
- Research
- Commercialized
Therapy Outlook (Revenue, USD Billion; 2018-2028)
- CAR T-cell therapy
- T-cell receptor (TCR)-based
- Tumor infiltrating lymphocytes (TIL)-based
Indication Outlook (Revenue, USD Billion; 2018-2028)
- Hematologic Malignancies
- Lymphoma
- Myeloma
- Leukemia
- Solid Tumors
- Brain & Central Nervous System
- Liver Cancer
- Melanoma
- Others
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Regional Outlook (Revenue, USD Billion; 2018-2028)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- U.K.
- France
- Italy
- Spain
- Sweden
- BENELUX
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- U.A.E.
- South Africa
- Israel
- Rest of MEA
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