NEW YORK (Reuters Health) - Treatment with the commonly used over-the-counter drug ibuprofen (Motrin, Advil), may reduce the impairments in thinking ability that often accompany severe liver disease, findings from an animal study suggest.Ibuprofen is an anti-inflammatory agent that belongs to a group of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). Previous research has suggested that inflammation plays a key role in the development of brain impairments caused by liver disease, referred to as “hepatic encephalopathy.”