CAMBRIDGE, Mass.--(BUSINESS WIRE)--Helicos BioSciences (Nasdaq:HLCS), a life science company focused on innovative genetic analysis technologies, announced today a formal collaboration with Dr. Victor Ambros to apply the quantitative power of True Single Molecule Sequencing (tSMSTM) to develop a single assay to characterize known species of microRNA (miRNA) as well as discover new non-coding RNAs.