Gentium S.p.A. Reports First Quarter Financial Results; Provides Financial and Clinical Update

VILLA GUARDIA (Como), Italy--(BUSINESS WIRE)--Gentium S.p.A. (NASDAQ: GENT) (the “Company”) today reported financial results for the quarter ended March 31, 2007. Highlights of the first quarter of 2007 and recent weeks as of June 7, 2007, include: Continued progress with the Phase III clinical trial in the U.S. evaluating Defibrotide as a potential treatment of severe Veno-Occlusive Disease (VOD) with Multiple Organ Failure (Severe VOD): this study has enrolled 39 patients. Progress with the Phase II/III clinical trials of Defibrotide in Europe for the prevention of VOD in children. This study is expected to be conducted in 35 centers and 130 patients have been enrolled in the trial.

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