The UltimaPro™ 25 that will be on display has a batch capacity of approximately 4 to 8.5 kg and is ideal for use in laboratories and for the contained production of low volume clinical or commercial drugs such as oncology products.
Containment
The mixing, drying and granulating highly potent compounds has always required the ultimate in containment to protect operators and avoid cross contamination. When fitted with the Hicoflex?flexible coupling that allows the contained feeding of highly sensitive or toxic powders, operators can work in shirt sleeves at safe exposure levels with no need for cumbersome personal protection equipment. Additionally, the UltimaPro™ can be equipped with several features to optimise the containment of toxic products: Product feed and discharge ports can be equipped with Buck® high containment split butterfly valves, and upon request, even with isolator boxes.
The UltimaPro™ 25 on display at Interpack will be fitted with a Lighthouse Probe™ (LHP) that monitors blend homogenity, granule formulation (particle size), liquid distribution and drying. Using the LHP avoids the need for sampling and enables full containment to be maintained throughout the process.
Cleaning and solvent recovery
The UltimaPro™ is equipped with a very efficient system to recover more than 99% of organic solvents used in the process. Recovering solvents efficiently is often as important as the containment itself to prevent cross contamination and save valuable raw materials.
For cleaning, the UltimaPro™ can be supplied with a wide range of washing-in-place and fully automated cleaning-in-place (CIP) options. CIP features include spray nozzles adapted for comprehensive cleaning of product feed, product filter, bowl, lid and discharge valve (for example retractable spray nozzles for the lid). Even downstream equipment such as a mill can be incorporated in the CIP system.
The containment system avoids the need for the production room to be cleaned at product changeover; this, with the automatic cleaning system, allows a complete change-over of the machine in less than two hours.
See the UltimaPro™ 25 on show at Interpack 2011 in Düsseldorf from 12-18 May on Stand number F24, Hall 8a.
Learn more about Single Pot processing at Interpack 2011 www.gea-ps.com/interpack
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