An international team of researchers led by investigators in the U.S. and Germany has shed light on the inner workings of the endocycle, a common cell cycle that fuels growth in plants, animals and some human tissues and is responsible for generating up to half of the Earth’s biomass. This discovery, led by a geneticist at Fred Hutchinson Cancer Research Center and reported Oct. 30 in Nature, leads to a new understanding of how cells grow and how rates of cell growth might be increased or decreased, which has important implications in both agriculture and medicine.