BERKELEY, Calif., Nov. 14 /PRNewswire/ -- The first human PCR primer set for genome-wide splice variant detection was launched today by Jivan Biologics, a privately held company located in Berkeley, CA. Using Jivan’s splice variant specific PCR primers, scientists can quickly identify changes in RNA splicing for human genes of interest. Scientists can discover new splice isoforms by sequencing unexpected PCR products.
“Jivan’s genome-wide PCR primer set is another industry first, as well as a pioneering solution to one of the great challenges in the post-genomic era,” said Subha Srinivasan, PhD, CEO of Jivan Biologics. “It complements Jivan’s splice array product line by making it easier for scientists to follow up on their discoveries.”
Customers for Jivan’s TransExpress(TM) splice arrays can order the corresponding PCR primer pairs for oligonucleotide probes on any TransExpress(TM) array. Each PCR primer pair spans an exon junction or alternately spliced site. Alternatively, researchers can directly order PCR primers for genes and splice variants of interest, bypassing microarray screening entirely.
A single microarray experiment often identifies many probes differentially expressed between disease and normal samples. Quantitative PCR is the method of choice to validate these potential biomarkers for use as diagnostics or drug targets. But designing PCR primers can be laborious, especially when the biological complexity of RNA splicing is taken into account, slowing the translation of genomic information into the clinic. Jivan’s genome-wide PCR primer set simplifies and accelerates this process.
To order Jivan’s PCR primers for alternate splicing, visit http://www.jivanbio.com or http://www.alternatesplicing.com.
Jivan Biologics empowers scientists with new insight by providing a full catalogue of splice variant arrays to benefit all stages of the drug development pipeline: biomarkers in blood, diagnostics, target validation, toxicology and basic research.
Contact: Jonathan Bingham jbingham@jivanbio.com +1-415-425-4115
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Jivan Biologics
CONTACT: Jonathan Bingham, Jivan Biologics, +1-415-425-4115,jbingham@jivanbio.com
