Conjugated polymer nanoparticles (CPN) are fluorescence emitting entities that are utilized in bio imaging, research & development, and photo optics.
Conjugated Polymer Nanoparticles Market: Introduction
- Conjugated polymer nanoparticles (CPN) are fluorescence emitting entities that are utilized in bio imaging, research & development, and photo optics. CPNs comprise light emitting polymers at the core and are encapsulated with hydrophilic polymer coating. Fluorescent imaging enables the real-time structural and functional study and visualization of cellular and molecular entities, without interfering the biological processes.
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- These imaging and visualization techniques are highly sensitive and tunable as per requirements, as compared to conventional imaging techniques. These factors have led to high expectation and preference for fluorescent imaging and visualization techniques. Fluorescent organic dye probes have been in used in bio imaging and R&D applications; however, these pose concerns such as low stability and photo bleaching. CPNs, on the other hand, offer high photoluminescence quantum yield often termed as brightness, better stability, rapid emission rate, and non-blinking behavior.
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Key Drivers, Restraints, and Opportunities of Global Conjugated Polymer Nanoparticles Market
- Conjugated polymer nanoparticles are available in various colors in the range of 450 nm to 680 nm. This wavelength augments deep penetration of light and high sensitivity. CPNs offer better luminance and bio-compatibility. These can be easily conjugated with biological or molecular entities such as antibodies, oligosaccharides, and peptides, which can aid in targeted imaging and visualization of cellular and molecular entities. Several suppliers are offering pre-conjugated CPNs with biological molecules such as antibodies. For instance, Stream Bio Ltd. has introduced streptavidin conjugated CPNs. These features have expanded the usage of CPNs in applications such as flow cytometry, cell imaging, immunohistochemistry, immuno cytometry, ELISA, and Western Blotting. Certain CPNs are also available with iron oxide molecules at the core, which helps visualization in magnetic resonance imaging (MRI). It further assists in manipulation and purification using magnets.
- However, adoption of conjugated polymer nanoparticles is low, owing to small number of suppliers, cumbersome production process, and lack of infrastructure. Increase in R&D expenditure for scientific studies by public and private sectors and a rise in access to these advanced technologies are anticipated to fuel the adoption of CPNs in the near future.
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North America to Capture Major Share of Global Conjugated Polymer Nanoparticles Market
In terms of region, the global conjugated polymer nanoparticles market can be segmented into North America, Europe, Asia Pacific, and Rest of the World. High rate of adoption of technologically advanced clinical research tools and high R&D expenditure by public and private sectors in the U.S. are anticipated to fuel the conjugated polymer nanoparticles market in North America. Europe is projected to account for a significant share of the global market owing to well-established healthcare infrastructure and large base of pharmaceutical and biotechnology industries in the region. Increase in public and private sector investment in the development of healthcare and R&D infrastructure in emerging markets, such as China and India, is expected to augment the market in Asia Pacific during the forecast period.
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Key Players Operating in Global Conjugated Polymer Nanoparticles Market
There are limited number of suppliers of conjugated polymer nanoparticles in the global market. Moreover, several public sector universities and research institutes invest in the development of new CPNs.
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