CAMBRIDGE, Mass.--(BUSINESS WIRE)--June 14, 2006--CombinatoRx, Incorporated (NASDAQ: CRXX - News) announced today that certain members of its senior management team, including Alexis Borisy, President and CEO; Robert Forrester, EVP and Chief Financial Officer; Jan Lessem, EVP and Chief Medical Officer; Daniel Grau, SVP, Commercial Operations and Curtis Keith, SVP, Research, have adopted prearranged stock trading plans pursuant to Rule 10b5-1 of the U.S. Securities Exchange Act of 1934. The plans adopted by these executive officers are effective until January 31, 2010 and may result in sales by these officers of CombinatoRx common stock at various times during the term of the plans at various predetermined sale prices. The timing of sales and number of shares of common stock actually sold under the plans will depend on the performance of CombinatoRx common stock during the term of the plans. The plans were adopted by these executive officers for personal financial reasons including asset diversification.