Callisto Pharmaceuticals Announces Licensing Of A New Class Of Cancer Drugs With A Novel Mechanism Of Action, Showing Potent Antitumor Activity

NEW YORK--(BUSINESS WIRE)--Jan. 25, 2006--Callisto Pharmaceuticals, Inc. (AMEX: KAL)(FWB:CA4), a developer of new drug treatments in the fight against cancer and other major health threats, has announced that it signed an agreement with The University of Texas M. D. Anderson Cancer Center (“M.D. Anderson” or “MDACC”) for the licensing of a new class of cancer drugs called Degrasyns for development as anti-cancer agents. The novel anti-cancer activity of these analogs, developed by scientists at M. D. Anderson, relates to their ability to selectively degrade key proteins that are involved in tumor cell proliferation and survival. So far this degradation appears to be specific for C-MYC, BCR-ABL and JAK2, all important targets for a wide range of important tumors.

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