Fluorescent probes, also known as fluorophores, are molecules that absorb light of a specific wavelength and emit light of a different wavelength
New York, April 16, 2019— As a trust-worthy supplier for chemicals widely applied in drug discovery, chemistry and life science, BOC Sciences’ management recently decides to update its Fluorescent Probes list for digital imaging, which allow life science researchers to gain new insights in virtually all sub-disciplines.
Fluorescent probes, also known as fluorophores, are molecules that absorb light of a specific wavelength and emit light of a different wavelength (typically longer). Widely used to study biological samples, fluorescent compounds based on synthetic small molecules are powerful tools to visualize biological events in living cells and organisms. Ever since its discovery in the late nineteenth century, efforts have been made to "see" the behaviors of specific biomolecules in living systems by using these dyes as labels.
Fluorescent compounds could be used alone or bonded to molecules to create fluorescent probes. “There are generally four types of fluorophores, namely, organic dyes, fluorescent proteins, quantum dots, and biological structures suitable for label-free imaging. There is a broad selection of fluorophores, which offers multiple choices and abundant possibilities in applications in life science and fundamental research, depending on their properties like biocompatibility, intensity, quantum yield, excitation and emission wavelength, fluorescence lifetime, size and the interaction with substances,” says Prof. Jones, a senior scientist from BOC Sciences. “Among their myriad of uses, fluorescent probes are employed to detect protein location and activation, identify protein complex formation and conformational changes as well as monitor biological processes in vivo.”
With this move, approximately 400 to 500 fluorescent probes are updated and can fall into the following categories: Cell and Organelle Stains, DNA Stains, Fluorescent Enzyme Substrates, Ion Indicators and Sensors, pH Indicators.
“Thanks to the development in fluorescent labeling, and thanks to the ability to fuse a genetically encoded fluorescent probe to an almost-unlimited variety of proteins, scientists have been enabled to investigate signaling pathways and see with unprecedented detail what previously cannot be seen, for example, the movement of intracellular proteins in living cells. This ability is even more powerful when when coupled with powerful widefield fluorescence and confocal microscopy techniques,” added Prof. Jones later on.
For more information about BOC Sciences’ fluorescent probes products, please visit https://www.bocsci.com/fluorescent-probes-list-245.html.
About BOC Sciences
Except for a comprehensive collection of featured products such as inhibitors, metabolites, impurities and natural compounds, BOC Sciences also provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery, including custom synthesis of chemicals that are not in stock, isotope labeling service, antibody drug conjugates, chiral synthesis and resolution, as well as analytical services, etc.
Media Contact
Linna Green
Marketing Specialist
