Avanti Therapeutics Introduces Aayush Biosphere - Power of Clinical Outcome Based Architecture Industry’s First Unified Therapeutic Drug Development Platform

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Germantown, Maryland – October, 1 0 , 20 13 – Avanti Therapeutics today unveiled an evolutionary new therapeutic drug development a rchitecture, innovative services and an open ecosystem of best in class partners to help biopharmaceutical companies develop next - generation clinical outcome focused therapeutics that unleash the full power of clinical functionalization . With today’s announcement, Aanti Therapeutics is delivering on the promise of clinical outcome through Unified therapeutic development - an architecture that bridges the silos in the drug development into one unified architecture using industry standard te chnologies. Key to Avanti ‘s approach is the Aayush Biosphere, which seamlessly integrates a theraputic drug core, unified functional fabric and clinical function interfaces in a single, integrated platform that can reduce therapeutic development infrastruc ture costs and complexity, help extend capital assets and improve business agility well into the future.

Today’s announcements extend Avanti ‘s unified therapeutic development portfolio and are a critical step in the company’s Programmable logic therapeutic s strategy. To help drug developers accelerate the transition to the Unified therapeutic development architecture, Avanti Therapeutics is paving the way with a comprehensive suite of new Unified development services . In addition, Avanti Therapeutics today announced collaboration with industry leaders on the Aayush Biosphere and architecture.

The Aayush Unified Therapeutic Development Platform : Based on industry standards, the Unified Therapeutic Development Platform is a new drug development model that uses integrated management and combines a " develop once” unified functional fabric with an industry standard clinical outcome based functionalization platform to optimize clinical outcome , reduce therapeutic drug development total overall cost, and provide dynamic resource provisioning for increased business agility and long term sustai nability .

o Reduces total cost of ownership: up to 9 0 percent reduction in capital expenditures (CAPEX) and up to 7 0% reduction in operational expenditures (OPEX).

o Improves drug pipeline productivity and improves business agility: provision infrastructure an d technical resources in days instead of months . Shifts the focus from development maintenance to portfolio innovation

o Increases scalability without added complexity: managed as a singl e system, whether it has one, multiple or diverse therapeutic portfolio s with thousands of clinically relevant functionalities .

o Improves developmental Efficiency: significantly reduces technology and technical expertise costs

o Provides interoperability and investment protection through industry standards - based infrastructure t hat is future - proof

Innovative Design for Next Generation programmable logic therapeutics

Taking a clean sla te architectural approach to therapeutic drug development infrastructure, Avanti Therapeutics today introduced the Aayush Biosphere - Unified Therapeutic Development Platform which therapeutic API core , clinical functions and stimuli - responsive on demand drug release into a scalable, modular architecture that is managed as a single system. The Unified therapeutic development platform is the firs t offering in a new family of products which complements the Avanti’s multifunctional therapeutics portfolio. Key Unified Therapeutic Development Platform element s include:

o Therapeutic C ore : - Avanti Therapeutics designed an entirely new class of system to manufacture nanoparticle core which incorporates the drug molecules based on the biomolecular properties (the next generation modular hybrid plasma reactor ). The Avanti’s therapeutic cores offer patented hybrid plasma technology to support divers e group of single and combination drugs allow significantly more therapeutic molecules per core .

o Unified Functional Fabric - The Avanti Unified functional fabric provides support for a unified fabric over a low - latency, lossless, clinical functionalization foundation. This functional foundation consolidates what today are separate formulation processes : active targeting ( Zip Code specificity ), enhanced availability (S tealth functionality ) and stimulli - responsive on demand drug release . This lowers costs by reducing the number of processes and technology dependence .

o Clinical function interfaces - The Aayush BioSphere unleashes the full potential of clinical outcome based functionalization , by enhancing the scalability, performance and operational control of clinical environments.

o Single Pane of Window Management - Management is uniquely integrated into all the components of the system, enabling the entire solution to be managed as a o Single Pane of Window Management - Management is uniquely integrated into all the components of the system, enabling the entire solution to be managed as a

? Open Partner Ecosystem – Avanti Therapeutics is collaborating with an open ecosystem of industry leaders to help stimulate technology innovation, augment next generation of therapeutic development , and accelerate market adoption of Unified d rug development . More details on these partners available here .

About Avanti Therapeutics

Avanti Therapeutics is a leading innovative technology - based biopharmaceutical company based in Germantown, Maryland, that develops and commercializes programmable logic therapeutics for the treatment of serious medical conditions. Avanti Therapeutics has a diverse product portfolio with product candidates in development in areas of high unmet me dical need, including hypercholesterolemia, oncology, CNS diseases, regenerative medicine and infectious diseases. Avanti Therapeutics has developed Aayush Biosphere - a unified therapeutic development platform – for clinical outcome based development of ne xt generation of Therapeutic drugs. For additional information about the company, please visit www.avantitherapeutics.com .

Contact Information:

Jenny Smith

Corporate Communications

202 - 677 - 5426

Jenny.smith@avantitherapeutics.com

SOURCE

Avanti Therapeutics, Inc.

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