BRIDGEWATER, N.J., July 27 /PRNewswire-FirstCall/ -- Sanofi-aventis announced today that Allegra-D(R) 24 Hour (fexofenadine HCl 180 mg/pseudophedrine HCl 240 mg) Extended-Release Tablets are now available for the treatment of seasonal allergy symptoms with nasal congestion in adults and children 12 years of age and older. Allegra-D 24 Hour provides allergy patients with the power of once-daily Allegra (fexofenadine HCl) 180 mg, combined with 24-hour relief from nasal congestion, in a convenient, once- daily tablet. Allegra-D 24 Hour is an addition to the Allegra(R) family of non-sedating and non-impairing products available for the treatment of seasonal allergy symptoms.
More than 40 million adults and children in the United States suffer from seasonal allergies and associated symptoms, such as nasal congestion, watery eyes, runny nose, sneezing and itchy throat. In fact, 9 out of 10 allergy patients experience congestion and consider it the most frustrating symptom. These symptoms are caused by the body’s reaction to allergens and typically occur in the spring and fall when large amounts of allergens, such as pollen, are in the air.
Allegra-D 24 Hour utilizes a controlled-release technology that provides a smooth delivery of pseudoephedrine over the entire dosing period, providing 24-hour nasal congestion relief in a convenient once-a-day dosage.
About Allegra Line of Products
Allegra offers an extensive family of products to provide patients with greater convenience and flexibility in treating their different seasonal allergy needs (Allegra 30 mg and 60 mg twice daily, Allegra 180 mg once daily, Allegra-D 12 Hour (fexofenadine HCl 60 mg/ pseudoephedrine HCl 120 mg) Extended-Release Tablets [for twice daily dosing] and Allegra-D 24 Hour).
The side effects with Allegra 180 mg for seasonal allergies are low and may include headache, cold or back pain. The side effects for Allegra 60 mg for seasonal allergies are low; less than 3% of people experience cold or flu, nausea, menstrual pain or drowsiness. The side effects for Allegra 30 mg are low and may include headache, cold, coughing or accidental injury.
Side effects with Allegra-D 12 Hour and Allegra-D 24 Hour were similar to Allegra 60 mg alone (headache, insomnia or nausea) and Allegra 180 mg alone (headache, cold or backache) respectively. Due to the decongestant (pseudoephedrine) component in both Allegra-D 12 Hour and Allegra-D 24 Hour, these products must not be used if you: are taking an MAO inhibitor (a medication for depression) or have stopped taking an MAO inhibitor within 14 days; retain urine; have narrow-angle glaucoma; have severe high blood pressure or severe heart disease. Side effects with pseudoephedrine may include nervousness, restlessness, dizziness, or insomnia. Headache, drowsiness, increased heart rate, palpitations, increased blood pressure, and abnormal heart rhythms have been reported. You should also tell your doctor if you have high blood pressure, diabetes, heart disease, glaucoma, thyroid disease, impaired kidney function, or symptoms of an enlarged prostate such as difficulty urinating.
For Allegra product information please log onto: http://www.aventis-us.com/PIs/allegra_TXT.html . For Allegra-D 12 Hour product information please log onto: http://www.aventis-us.com/PIs/allegra_d_TXT.html . For Allegra-D 24 Hour product information please log onto: http://www.aventis-us.com/PIs/allegrad24.pdf . About sanofi-aventis
The sanofi-aventis Group is the world’s third largest pharmaceutical company, ranking number one in Europe. Backed by a world-class R&D organization, sanofi-aventis is developing leading positions in seven major therapeutic areas: cardiovascular, thrombosis, oncology, metabolic diseases, central nervous system, internal medicine, and vaccines. The sanofi-aventis Group is listed in Paris and in New York .
Forward Looking Statements
This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts. These statements include financial projections and estimates and their underlying assumptions, statements regarding plans, objectives and expectations with respect to future operations, products and services, and statements regarding future performance. Forward-looking statements are generally identified by the words “expect,” “anticipates,” “believes,” “intends,” “estimates,” “plans” and similar expressions. Although sanofi-aventis’ management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of sanofi-aventis, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. These risks and uncertainties include those discussed or identified in the public filings with the SEC and the AMF made by sanofi-aventis, including those listed under “Risk Factors” and “Cautionary Statement Regarding Forward- Looking Statements” in sanofi-aventis’ annual report on Form 20-F for the year ended December 31, 2004. Other than as required by applicable law, sanofi- aventis does not undertake any obligation to update or revise any forward- looking information or statements.
Sanofi-aventis Group subsidiaries in the United States include Sanofi- Synthelabo Inc., Aventis Pharmaceuticals Inc. and Sanofi Pasteur Inc.
Contact: Melissa Feltmann
908.243.7080 Melissa.feltmann@sanofi-aventis.com
sanofi-aventis Group
CONTACT: Melissa Feltmann, +1-908-243-7080,Melissa.feltmann@sanofi-aventis.com
Web site: http://www.sanofi-aventis.com/
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