Avalon Pharmaceuticals To Release First Quarter 2006 Financial Results On May 10, 2006

GERMANTOWN, Md., May 2 /PRNewswire-FirstCall/ -- Avalon Pharmaceuticals, Inc. (Nasdaq and ArcaEx(R): AVRX) today announced that it is scheduled to release financial results for the first quarter of 2006, on Wednesday, May 10, 2006 after the close of the U.S. financial markets. The Company will host a conference call on Thursday, May 11, 2006 at 8:00 a.m. Eastern Time to provide a company update and discuss the financial results for the quarter. Interested investors, analysts, members of the media and the general public can listen to the call live over the Internet from the investor section of the Company’s website or by dialing the numbers listed below.

Conference Call Details: ------------------------ Dial-In: 866-713-8307 (U.S.) 617-597-5307 (International) Passcode: 67310263

Webcast: Please go to www.avalonrx.com, Investors, within 15 minutes prior to the call and select the webcast link. The conference call replay will be available through June 30, 2006 on Avalon’s website (www.avalonrx.com).

About Avalon Pharmaceuticals

Avalon Pharmaceuticals is a biopharmaceutical company focused on the discovery and development of small molecule therapeutics. Avalon seeks to discover and develop novel therapeutics through the use of a comprehensive, innovative and proprietary suite of technologies based upon large-scale gene expression analysis which it calls AvalonRx(R). Avalon Pharmaceuticals was established in 1999 and is headquartered in Germantown, Maryland.

Avalon Pharmaceuticals

CONTACT: Gary Lessing, Executive Vice President and CFO of AvalonPharmaceuticals, Tel: +1-301-556-9900, or Fax: +1-301-556-9910, or Email:info@avalonrx.com

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