Soaring Demand for High-Fidelity PCR to Foster PCR Master Mix Sales: Fact.MR

Rising cases of genetic disorders and infectious diseases is generating the demand for a highly advanced real-time PCR master mix

Fact.MR, Rockville MD: Fact.MR is conducting an ongoing research study on global PCR master mix, which projects a steady growth in the forthcoming years. According to the study, the market is expected to have an upward trajectory backed by the increasing prevalence of genetic diseases recorded across the globe. Technological advancement and penetration of Artificial Intelligence used in developing real-time projects for the treatment of infectious diseases is aiding the growth of the market.

According to Fact.MR, increasing demand of high fidelity PCR master mix for high precision to record the high sample for gene analysis and from biotechnological institutes is creating a domino effect on the growth of PCR master mix. Significant use of high-fidelity PCR in PCR amplification of DNA fragments is surging the demand.

Biotechnological institutes and research centers are frequently using high-fidelity PCR for the ongoing research study of cloning and mutagenesis which is of high importance for application in which the DNA sequence need to be corrected after amplification. Hence, furthering the demand.

“Leading industry players are increasing the R&D activity to cater the demand of technologically advanced and high precision high-fidelity DNA polymerases from the healthcare industry and research institutes which is escalating the growth of the market ,” says the Fact.MR analyst.

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Key Takeaways

  • US to lead the North American market, owing to increasing R&D activities for the development of new drugs
  • Germany to emerge as a potential market through 2031, leading Europe to account for largest market share
  • India and China expected to witness significant growth owing to the growing incidences of genetic diseases
  • Japan anticipated to witness a steady growth backed by the increasing demand of real-time PCR master mix
  • High-fidelity master mix expected to dominate the market
  • PCR amplification of DNA fragments is likely to be the most common and widely used application
  • Research centers expected to be the primary end-users attributed to the high R&D activities being carried out in healthcare sector

Prominent Drivers

  • Increasing cases of infectious diseases and genetic disorders to propel the market growth
  • Technological investments, generous funds and grants to create growth opportunities for the PCR manufacturers
  • Soaring demand for biomarkers profiling for disease diagnostics to bolster the PCR master mix demand
  • Preference for genome-based drug discovery from plant-derived drug discovery to boost PCR master mix sales

Key Restraints

  • Technical limitation and high cost associated with PCR techniques to hamper the growth
  • Stringent regulations and implementation of MIQE guidelines for real-time PCR experiments to pose a challenge for the market

Discover more about the PCR master mix market with figures, data tables and the table of contents. You will also find detailed market segmentation on

Competitive Landscape

Key PCR master mix manufacturers profiled by Fact.MR include Merck KGaA, Roche, Thermofisher Scientific Inc., Promega Corporation and Bio-Rad Laboratories among others. As evaluated by Fact.MR, manufacturers are focusing on developing new model in order to sustain and recover after the pandemic outbreak.

In 2020, Meridian launched High-Specificity Pfu HS Mix, a high-fidelity PCR master mix containing an aptamer to develop a reversible, temperature-dependent hot-start and buffer, made for low GC bias amplification. The 3’–5′ proofreading exonuclease activity of High-Specificity HS Mix makes it ideal, the company says, for target enrichment, NGS library amplification, and cloning applications.

Additionally, ThermaGenix launched the collaboration with Millipore Sigma, in 2018, for the sale of ThermaStopTM, ThermaGoTM and ThermaStop-RT. Due to their unique chemistries, these reagents improve the specificity and fidelity of Taq Polymerase and Reverse Transcriptase -especially in applications such as qPCR, rt-PCR, and preparation of DNA amplifications prior to Next-Generation Sequencing.    ThermaGenix PCR reagent products are now available for purchase through Millipore Sigma’s Global Sales organization and through e-commerce platform.

More Insights on the PCR master mix Market

A recent study by Fact.MR gives a detailed analysis on the global PCR master mix market. In order to understand the global market potential, its growth, and scope, the market is segmented on the basis of product type (high-fidelity PCR master mix, real time qPCR master mix, and others), application (PCR application of DNA fragments, high throughput PCR, DNA labeling, and others), end-user (research centers, biotechnology institutes, and others), and regions (North America, Latin America, Europe, Asia Pacific excluding Japan, Japan, CIS & Russia, and Middle East and Africa)

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