Xilis Announces Formation of its Scientific Advisory Board
Company developing breakthrough clinically-predictive patient tumor avatar platform with native tumor–immune biology to accelerate drug discovery and development and revolutionize patient care
DURHAM, N.C. , Dec. 15, 2022 /PRNewswire/ --Xilis, Inc., a pioneering biotech company advancing its proprietary MicroOrganoSphere™ (MOS) Platform to accelerate drug discovery and development and advance functional precision medicine for cancer patients, today announced the addition of four members to its newly formed Scientific Advisory Board (SAB). Xilis' MOS Platform is the first patient tumor avatar platform designed to predict patient drug response in the clinic and recapitulate the complex tumor-immune biology necessary to further drug discovery and development of immuno-oncology, targeted, and cell therapies with high confidence of clinical success.
"With major Pharma collaborations and clinical trials underway, we have reached an inflection point in our growth," said Dr. Xiling Shen, Co-founder and CEO of Xilis. "Right now, most oncology drugs fail clinical trials, and the majority of patients are taking drugs that won't provide long-term benefits. We believe our technology has the potential to radically change the paradigm in cancer drug discovery for the pharmaceutical industry by testing their new drugs on MOS, predicting likely patient drug response in the clinic, and determining which drugs will or won't work before starting clinical trials. We are pleased to have such an esteemed group of experts to advise us as we seek to shape a cancer-free future."
The new members of the Xilis Scientific Advisory Board include:
"Big Pharma is eager to develop the next generation of cancer treatments, but one of the biggest hurdles to overcome is identifying which new drugs have the highest potential to be effective," said Dr. Mike Varney, Chair of the Xilis Scientific Advisory Board. "Xilis technology represents a quantum leap in
re-defining a more rational drug development paradigm with improved economics for drug development."
Xilis recently announced an $89M Series A with esteemed investors including Mubadala Capital Management, GV (formerly Google Ventures), EQT Life Sciences, Felicis Ventures, Two Sigma Ventures, Pear Ventures, FPV Ventures, Catalio Capital Management, 8VC, Alexandria Venture Investments, Duke Capital Partners, and other strategic partners.
Founded in 2019 by Dr. Xiling Shen, Dr. David Hsu, and Dr. Hans Clevers, Xilis is based on decades of biomedical, oncology, and stem cell research by its three co-founders. Dr. Clevers, a Breakthrough Prize winner, is the inventor and pioneer of organoid technology. Dr. Shen is an engineer with a strong track record of successful innovation at the intersection of biology and engineering, and multiple previous appointments in academia, including at Duke University. Dr. Shen recently left Duke University and now serves as CEO of Xilis. Dr. Hsu is an oncologist and medical professor at Duke University, and an expert in precision medicine. The Xilis team has developed the scalable MOS technology to analyze patients' own tumors in their native microenvironment – a breakthrough achievement.
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