Precision NanoSystems has launched the NanoAssemblr™ Scale-Up system to support the clinical development of nanomedicines. This latest addition to the NanoAssemblr range is designed for the manufacture of clinical trial material in GMP environments, and will support the production of novel medicines, including siRNA, mRNA and CRISPR/Cas9 therapeutics.
The NanoAssemblr Scale-Up system features the same proprietary microfluidic mixing technology as the company’s preclinical instruments – the NanoAssemblr Benchtop™ and Blaze™ – providing seamless scale-up following formulation development. Its compact, modular design uses a fully disposable fluid path with multiple microfluidic mixers connected in parallel to produce a single large volume batch in less time, and is ideally suited to manufacturing batch volumes sufficient for clinical trials.
“The NanoAssemblr Scale-Up system is designed to provide customers with a customizable, modular platform for the cGMP manufacture of high quality nanomedicines,” commented Ray Lockard, Vice President of Pharmaceutical Operations at Precision NanoSystems. “By using the same underlying technology as the rest of the NanoAssemblr instrument portfolio, this will allow researchers to accelerate product development from discovery to the clinic and, ultimately, help to realize the potential for novel therapeutic modalities, such as genome editing and mRNA-mediated protein expression.”
The NanoAssemblr Scale-Up system can be viewed at Precision NanoSystems’ facilities in Vancouver, BC, and South San Francisco, CA. For more information, visit www.precisionnanosystems.com/scale-up
About Precision NanoSystems
Precision NanoSystems Inc. (PNI) creates innovative solutions for the discovery, development and manufacture of novel nanoparticles for use as medicines and in medical research. PNI’s proprietary NanoAssemblr Platform enables the rapid, reproducible, and scalable manufacture of next generation nanoparticle formulations for the targeted delivery of therapeutic and diagnostic agents to cells and tissues in the body. PNI provides instruments, reagents and services to life sciences researchers, including pharmaceutical companies, and builds strategic collaborations to revolutionize healthcare through nanotechnology. For more information, visit www.precisionnanosystems.com.
