Precision NanoSystems Announces New Cell Therapy Reagent for Lipid Nanoparticle -based mRNA Delivery to T Cells
VANCOUVER, BC, April 20, 2021 /PRNewswire/ - Precision NanoSystems (PNI), a global leader in innovative solutions for genetic medicine development, today launched the GenVoy-ILM™ T Cell Kit for mRNA to enable lipid nanoparticle (LNP)-based ex vivo gene transfer. Scientists can now use mRNA-LNP to efficiently and reproducibly generate high yields of engineered primary human T cells using a simple workflow.
The GenVoy-ILM T Cell Kit for mRNA uses LNP designed to exploit endogenous uptake pathways to efficiently deliver mRNA into activated human primary T cells to mediate titratable, uniform protein expression levels with high cell viability. The mRNA-LNP are also compatible with established T cell culture media allowing rapid integration into existing workflows. The combination of non-disruptive mRNA delivery technology and seamless integration with cell culture protocols eliminates cell recovery times post-treatment to accelerate the production of T cell therapies.
"The COVID-19 mRNA-LNP vaccines have demonstrated the power of lipid nanoparticle technology for the rapid development of highly effective genetic medicines" said Dr. James Taylor, CEO & cofounder of PNI. "PNI believes that LNP technology can also accelerate the development of transformative cell therapies and we are thrilled to launch a LNP reagent kit specifically designed for the efficient delivery of mRNA into T cells using PNI's proprietary GenVoy-ILM™ delivery platform."
Dr. Angelo Cardoso, Director of the Laboratory for Cellular Medicine at the Beckman Research Institute at City of Hope, also expressed excitement about PNI's launch of GenVoy-ILM T Cell Kit for mRNA, "LNP designed for defined cell types open new opportunities for the manufacture of gene-edited cell therapies and, hopefully in the future, in vivo gene targeting."
Learn more about the GenVoy-ILM T Cell Kit for mRNA by registering for our upcoming webinars on May 6th and May 11th. And Join us at the American Society of Gene & Cell Therapy Annual Meeting for a PNI sponsored symposium "Accelerating Genetic Medicine Development with Lipid Nanoparticles" at 2-3:30 PM ET on May 13th, 2021.
Learn more about those events at https://www.precisionnanosystems.com/resources-and-community/learningpaths/events.
Learn more about Precision NanoSystems and the GenVoy-ILM T Cell Kit for mRNA at https://www.precisionnanosystems.com.
About Precision NanoSystems Inc. (PNI)
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SOURCE Precision Nanosystems