Global DNA methylation market size reached USD 7.79 billion in 2021 and is expected to register a revenue CAGR of 15.9% during the forecast period, according to latest analysis by Emergen Research.
Global DNA methylation market size reached USD 7.79 billion in 2021 and is expected to register a revenue CAGR of 15.9% during the forecast period, according to latest analysis by Emergen Research. The growing demand for epigenetic therapies, coupled with the large-scale commercialization of DNA methylation-based disease diagnostic tests and kits, is expected to drive market growth over the forecast period. Moreover, the rapid adoption of next-generation sequencing (NGS) technologies in drug development and clinical research is also anticipated to boost market growth.
The increasing demand for epigenetics-based research is also a key factor driving the market. Epigenetics is the study of functional and structural changes in the genome, which do not involve any alteration in the DNA sequence. These changes are transmitted to the daughter cells and affect gene expression without changing the DNA sequences. Methylation is one of the main epigenetic modifications that have been studied extensively over the past few years.
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DNA methylation is a process by which methyl groups are added to the DNA molecule. This results in the modification of gene expression and leads to the silencing of certain genes. It plays an important role in various cellular processes, such as cell differentiation, embryogenesis, genomic imprinting, and X-chromosome inactivation. In addition, DNA methylation is also known to be associated with various diseases, such as cancer, neurodegenerative disorders, and cardiovascular diseases.
However, concerns regarding lack of expertise and technical know-how and high cost associated with the technology are some of the major factors expected to restraint the growth of global DNA methylation market over the forecast period.
Some Key Highlights From the Report
- The reagents & kits segment held the largest share of the market in 2013 and is expected to grow at a rapid pace during the forecast period. This is due to the increasing demand for these products from academic research institutes and pharmaceutical & biotechnology companies.
- Based on service, the global DNA methylation market is segmented into library preparation, sequencing, and data analysis & interpretation services. The library preparation services segment accounted for the largest share of the market in 2017 owing to the increasing demand for high-quality library preparation services for next-generation sequencing.
- The bisulfite-conversion-based methods segment accounted for the largest share of the market in 2017 owing to the widespread adoption of this technology for DNA methylation analysis.
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- The cancer research segment accounted for the largest share of the market in 2017 owing to the increasing incidence of cancer and the growing need for early diagnosis and treatment.
- North America held the largest share of the global DNA methylation market in 2017 due to the presence of a large number of market players, the availability of advanced infrastructure for genomic research, and the increasing government funding for genomics research.
- Asia Pacific is expected to witness the highest growth rate during the forecast period owing to the increasing incidence of cancer, the growing need for early diagnosis and treatment, and the expanding base of the biotechnology and pharmaceutical industry in the region.
- Some major companies in the global market report include New England Biolabs, Merck KGaA, Pacific Biosciences, Inc., Thermo-Fisher Scientific, Inc., Illumina, Inc., Bio-Rad Laboratories, Inc., Sysmex Corporation, Abcam plc., F. Hoffmann-La Roche Ltd., and Diagenode Diagnostics S.A.
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Emergen Research has segmented the global DNA methylation market on the basis of technology, application, end-use, and region:
- Technology Outlook (Revenue, USD Billion, 2019–2030)
- Bisulfite DNA Modification
- Methylated DNA Immunoprecipitation
- High-Resolution Melt Analysis
- Others
- Application Outlook (Revenue, USD Billion, 2019–2030)
- DNA Sequencing
- Oncology Research
- Microarray
- Immunological Assays
- Others
- End-Use Outlook (Revenue, USD Billion, 2019–2030)
- Biotechnology Industry
- Pharmaceutical Industry
- Academic Institutions
- Research Laboratories
- Others
- Product Outlook (Revenue, USD Billion, 2019–2030)
- Enzymes
- Reagents
- Kits
- Instruments and Consumables
- Others
- Regional Outlook (Revenue, USD Billion, 2019–2030)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- U.K.
- Italy
- Spain
- Benelux
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of APAC
- Latin America
- Brazil
- Rest of LATAM
- Middle East & Africa
- Saudi Arabia
- UAE
- South Africa
- Turkey
- Rest of MEA
- North America
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