Discovery May Lead To Vaccine For All 4 Types Of Dengue, University of North Carolina Study

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Researchers have discovered a new target for human antibodies that may lead to a vaccine for all four types of dengue virus—and may also have potential for vaccine development for other diseases, including SARS and HIV. Creating a vaccine that protects people from the four types of dengue virus has frustrated scientists for decades. Using an experimental technique new to the dengue field, researchers found that a molecular hinge where two regions of a protein connect is where natural human antibodies attach to dengue 3 to disable it.

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