GENEVA, SWITZERLAND--(Marketwire - November 29, 2007) - Allosteric modulation company Addex Pharmaceuticals Ltd (SWX: ADXN) today confirmed that its major pre-IPO shareholders have entered into a second lock-up period whereby they have agreed that if they wish to sell shares of Addex then they will do so in a coordinated manner. Addex and each shareholder immediately prior to the initial public offering of 21 May 2007 entered into an individual lock-up agreement with the Global Co-ordinator, Lehman Brothers International (Europe), for a term of 360 and 180 days, respectively, from the first day of trading of the shares on the SWX Swiss Exchange. As described in the offering circular of 21 May 2007, all shareholders prior to the offering (except for Addex and the members of its current and former staff, but including the members of its executive management) have entered into a second lock-up agreement for another period of 180 days from the expiration of the first lock-up.