WATERTOWN, Mass.--(BUSINESS WIRE)--Acusphere, Inc. (NASDAQ: ACUS) today announced that it had completed the renegotiation of payment terms under certain intellectual property agreements. Payments due in the 12 months ending March 31, 2009 have been reduced by $3.5 million and shifted out by the same amount to later in 2009. The Company expects a full response letter from the FDA on its recently filed NDA for ImagifyTM (Perflubutane Polymer Microspheres) for Injectable Suspension, on or around the PDUFA date in Q1 2009.