REDWOOD CITY, Calif.--(BUSINESS WIRE)--A.P. Pharma, Inc. (NASDAQ:APPA), a specialty pharmaceuticals company, announced today that Michael O’Connell, its Chief Operating Officer and Chief Financial Officer, will be leaving the company on January 18, 2008. Mr. O’Connell originally joined A.P. Pharma in 1992 as Vice President and Chief Financial Officer. In 2000 he was named President and Chief Executive Officer, and served in that capacity until departing in October of 2006 on medical leave. He rejoined the management team in mid-2007 in his present capacity. Upon his resignation, Mr. O’Connell will be entitled to the benefits of a retention agreement that are payable due to his not being reappointed to the position of President and Chief Executive Officer.