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Tristan Manalac

Tristan Manalac

Contributing Writer | News

Tristan is an independent science writer based in Metro Manila, with more than eight years of experience writing about medicine, biotech and science. Being formally trained in molecular biology, he once dreamed of collecting degrees and starting his own lab. But these days, he finds his greatest joy in a bottle of beer and a beautiful sentence. He can be reached at tristan.manalac@biospace.com, tristan@tristanmanalac.com or on LinkedIn.

Problems and Challenges. Businessman stands on question mark
Earnings
Future of BMS’ Cobenfy Still in Limbo After Phase III Fail
Bristol Myers Squibb tested Cobenfy as an adjunctive treatment with atypical antipsychotics for schizophrenia in the Phase III ARISE study, which earlier this year failed to demonstrate significant symptom improvement.
July 31, 2025
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2 min read
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Tristan Manalac
woman hand is removing hair from blue brush. A Hair care.
Immunology and inflammation
AbbVie Carves Out Niche for Rinvoq With ‘Impressive’ Alopecia Areata Data
Rinvoq’s efficacy in alopecia areata is “impressive,” according to Guggenheim analysts, who said the drug could have a competitive edge over other JAK inhibitors in the space.
July 31, 2025
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2 min read
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Tristan Manalac
Female hand holds notebook with brain on yellow background
Alzheimer’s disease
Amyloid Return ‘Slow’ After Stopping Lilly’s Kisunla
Long-term extension data presented at the Alzheimer’s Association International Conference showed amyloid plaque reaccumulation remained slow at up to 2.5 years of follow-up in patients who were taken off of treatment with Eli Lilly’s anti-amyloid antibody.
July 31, 2025
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2 min read
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Tristan Manalac
3d fatty liver disease isolated on pink background. 3d illustration render
MASH
Madrigal Makes Potential $2B+ Bet for CSPC’s GLP-1 Pill
Madrigal will study SYH2086 in combination with Rezdiffra for metabolic dysfunction-associated steatohepatitis, aiming for clinical trials in early 2026.
July 30, 2025
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2 min read
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Tristan Manalac
Mental health, illness ,brain development ,medical treatment concept, messy lines of thinks in human head , vector illustration
Alzheimer’s disease
Biogen, Eisai’s Leqembi Slows Alzheimer’s Progression Through 4 Years of Treatment
Long-term data presented at the Alzheimer’s Association International Conference show Leqembi can help patients stay in the earlier stages of Alzheimer’s disease as compared to the condition’s natural progression.
July 30, 2025
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2 min read
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Tristan Manalac
Susan Monarez speaking to a senator at her confirmation hearing as CDC director
CDC
Susan Monarez Confirmed by Senate as CDC Director
Monarez is the first CDC director to be confirmed by the Senate under a new 2023 law and will be the first person without a medical degree to assume leadership of the agency in more than 70 years.
July 30, 2025
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2 min read
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Tristan Manalac
Poznan, Poland - 5 October 2024: GSK -Glaxosmithkline headquarters office building in Poznan.
Earnings
GSK to Inject ‘Tens of Billions’ in US Amid Trump’s Tariffs, Pipeline Reshuffles
CEO Emma Walmsley maintained that continued investment in the U.S. is a priority for the pharma to ensure its medicines for the country are supplied domestically.
July 30, 2025
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2 min read
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Tristan Manalac
businessman on dollar boat with storm and lightning
Business
Four Scrappy Biotechs Braving the Stormy Market Alone
Against steep odds and well-established paradigms, these four companies have successfully been commercializing their products on their own.
July 30, 2025
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7 min read
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Tristan Manalac
Facade of AstraZeneca's office in Shanghai, China
Earnings
AstraZeneca CEO Says World ‘Needs to Share’ in Global Pharma R&D
Pascal Soriot’s comments came during AstraZeneca’s Q2 earnings call in regard to President Donald Trump’s newly announced European pharma tariffs. The company also announced estimate-beating earnings, with its cancer portfolio driving earnings despite clinical roadblocks.
July 29, 2025
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3 min read
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Tristan Manalac
Inclusion of new taxes into the price and increase in cost. Include inflation and costs for pricing. Increase in cost of electricity, fuel, increase in wages for workers or theft in the store.
Tariffs
15% Tariffs Come to Pharma in New EU Trade Deal
While some analysts forecast the tariffs could mean billions in additional industry expenditure, others expect the overall impact to be “manageable.”
July 29, 2025
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2 min read
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Tristan Manalac
Vaccines
RFK Jr. Looks to Overhaul ‘Broken’ Vaccine Injury Compensation Program
In a post on X, Health Secretary Robert F. Kennedy Jr. alleged that the Vaccine Injury Compensation Program has “devolved into a morass of inefficiency, favoritism, and outright corruption.”
July 29, 2025
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2 min read
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Tristan Manalac
Red and White Cartoon Spaceship Flying on Blue Background with Copy Space 3D Illustration
Startups
BMS, Bain Birth Biotech for Autoimmune Disorders
BMS is spinning out a new company with five immunology assets, including oral drugs being developed for systemic lupus erythematosus and plaque psoriasis, and $300 million in funds from Bain Capital.
July 29, 2025
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2 min read
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Tristan Manalac
Collage of a man hand giving a one hundred dollar bill to a woman hand on a yellow circle on a beige scratched background
Deals
GSK Bets Up To $12B for Multi-Program Cancer Pact With Hengrui
The star of GSK’s Hengrui partnership is the COPD candidate HRS-9821, which will complement the pharma’s respiratory pipeline that’s anchored by the anti-asthma drug Nucala.
July 28, 2025
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2 min read
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Tristan Manalac
Government
American Medical Association Urges RFK Jr. to Maintain Preventive Task Force
Health Secretary Robert F. Kennedy Jr. wants to remove all members of the USPSTF for being too “woke,” according to reporting by the Wall Street Journal. An HHS spokesperson, however, says no final decision has been made about the panel.
July 28, 2025
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2 min read
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Tristan Manalac
A concept of unfair social prejudice. The miniature men and a magnifying glass.
Duchenne muscular dystrophy
Sarepta Denies Latest Patient Death is Elevidys-Linked as FDA Launches Probe
Brazilian authorities said the death was unlikely to have been caused by Elevidys and was instead more in line with severe infection exacerbated by immunosuppression.
July 28, 2025
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2 min read
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Tristan Manalac
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