RESEARCH TRIANGLE PARK, N.C. & SHERBROOKE, Quebec--(BUSINESS WIRE)--June 21, 2006--Tranzyme Pharma, a leading biopharmaceutical company developing novel small molecule therapeutics for the treatment of gastrointestinal (GI) and metabolic diseases, announced today the appointment of Helmut Thomas, Ph.D., DABT, as the Company’s Senior Vice President of Research and Preclinical Development. In this position, he will assume primary responsibility for Tranzyme’s discovery research and early stage development efforts.