Synergys Biotherapeutics, a preclinical stage biotherapeutics company developing Vasculogenic Mimicry (VM)-blocking antibody fusion drugs for cancer treatment announced today the granting of its second Phase 1 Small Business Innovation Research (SBIR) award by the National Cancer Institute (NCI)
The fusion candidates were derived from A-TAP (Antibody-Targeted Anti-vascularization Payload) system that was pioneered by Drs. Joseph Rosenblatt, M.D., Professor and Chief of the Hematology Division and Seung-Uon Shin, Ph.D., Research Associate Professor, Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL. Synergys has established a long-term collaboration with Drs. Rosenblatt and Shin in developing the fusion candidates and exploring the molecular mechanism of VM inhibition in decreasing tumor burden and metastasis inhibition in cancer.
Regarding the award, Dr. Rosenblatt notes, “As a co-PI of the project, I am excited to note that our pioneering work on vasculogenic mimicry inhibition in cancer is being recognized by the SBIR review boards for its therapeutic potential, first for TNBC and now again for ovarian cancer. We look forward to continuing our collaboration with Synergys for the development of the antibody fusion molecules as new targeted therapeutics for various cancers.”
Dr. Rathin Das, PhD, CEO of Synergys said, “Receiving our second SBIR award from the NCI is both validation and endorsement of the VM-blocking A-TAP platform thereby providing significant impetus for utilizing it for the development of breakthrough treatment modalities for a variety of solid cancers.”
About Synergys Biotherapeutics
Synergys is an early stage company developing Vasculogenic Mimicry-blocking Antibody Fusion products for various cancers. The Company’s most advanced product candidate, Anti-EGFR‐TAP is currently in preclinical development for Triple Negative Breast Cancer. Additionally, a second candidate, Anti-HER2-TAP is being developed for ovarian cancer. Both candidates were derived from the technology termed A‐TAP (Antibody-Targeted Anti-Vascularization Payload). Synergys utilizes a virtual business model and works with various CROs and academic partners for the development of its therapeutic candidates.
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Contacts
Dr. Rathin Das
Chief Executive Officer
Synergys Biotherapeutics,Inc.
Ph: 925-575-0181;
email: rathindas@synergysbio.com, and visit
www.Synergysbio.com.
Source: Synergys Biotherapeutics
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