Single GFP-Expressing Cell is Basis of Living Laser Device, Massachusetts General Hospital Study

It sounds like something out of a comic book or a science fiction movie – a living laser – but that is exactly what two investigators at the Wellman Center for Photomedicine at Massachusetts General Hospital have developed. In a report that will appear in the journal Nature Photonics and is receiving advance online release, Wellman researchers Malte Gather, PhD, and Seok Hyun Yun, PhD, describe how a single cell genetically engineered to express green fluorescent protein (GFP) can be used to amplify the light particles called photons into nanosecond-long pulses of laser light.

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