WAYNE, Pa.--(BUSINESS WIRE)--Safeguard Scientifics, Inc. (NYSE:SFE), a holding company that builds value in growth-stage technology and life sciences companies, today announced that it will present at The Roth Capital Partners Semi-Annual Software Investor Conference at The Clift Hotel in San Francisco, CA on Thursday, December 13, 2007 at 7:00am PT (10:00am PT).