Novan Therapeutics’s Nitric Oxide Drug Candidate Inhibits Growth Of Papillomavirus In Translational Animal Model

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DURHAM, N.C.--(BUSINESS WIRE)--Novan Therapeutics, a clinical-stage biotech company focused on advancing nitric oxide therapies, announced today that Novan’s nitric oxide drug candidate SB206 was shown to inhibit papilloma growth in a preclinical animal study. About two-thirds of healthy American adults are infected with human papillomavirus (HPV), which constitutes a group of more than 100 genetically similar DNA viruses propagated primarily as sexually transmitted infections. While low-risk variants of HPV typically are associated with two types of papillomas – common warts and genital warts – high-risk strains of the virus are associated with cervical cancers, as well as cancer of the vagina, vulva, anus, rectum and penis. In total, high-risk strains of HPV account for approximately 5% of all cancers worldwide.

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