New large study reveals key role of genes in diabetes

The journal Scientific Reports has published today the results of a research study looking at the contribution of genetic variants, family history and obesity to the development of type 2 diabetes.

SAN SEBASTIAN. SPAIN

The journal Scientific Reports has published today the results of a research study looking at the contribution of genetic variants, family history and obesity to the development of type 2 diabetes.

The study included 7,258 people risk assessment and rationalized recommendations for preventive measures and personalized intervention was made possible thanks to the genomic tool DIABETESpredict, developed by Patia.

This test evaluates the genetic predisposition to type 2 diabetes through a simple DNA test that analyze 16 single nucleotide polymorphisms (SNP) associated with type 2 diabetes. The study, entitled “Influence of obesity, family history, and genetics on type 2 diabetes”, compared non-diabetic controls with diabetic patients in a hispanic population of 7,258 people.

“Type 2 diabetes is a complex disease. Some people have no family history of diabetes, yet they have genetic variations that predispose them to this condition. It is important to discern genetic variants from family history and obesity, and to know the contribution that each of these factors has in the pathology to provide physicians with better tools in the fight for prevention,” says MD, PhD. Mirella G. Zulueta, Medical Director of Patia.

About type 2 diabetes

The data on diabetes in the world reaches alarming figures. The pandemic is increasing on the planet, and the International Diabetes Federation (IDF) is gathering data that cannot be more discouraging. We have already surpassed the 425 million diabetics in the world. Research suggests that 1 out of 3 adults has prediabetes. Of this group, 9 out of 10 don’t know they have it. More than one in every 10 adults who are 20 years or older has diabetes. According to the American Diabetes Association 1.5 million Americans are diagnosed with diabetes every year. Diabetes remains the 7th leading cause of death in the United States in 2015.

Type 2 diabetes is a multifactorial pathology involving genetic factors, and environmental factors (nutrition, exercise, stress, sleep, etc.) that can be modified.

Discovering the genetic predisposition makes it possible to anticipate and define preventive measures, mainly focused on changing lifestyle habits related to diet and physical activity.

ABOUT PATIA www.patiadiabetes.com

Patia tackles diabetes. The company has developed a platform of solutions to prevent, manage and intervene in type 2 diabetes and gestational diabetes. Patia uniquely and cost-effectively integrates a set of high-performance genotyping tests with predictive algorithms, digital applications and lifestyle intervention.

Patia’s activity starts by translating the knowledge of large genetic studies on diabetes developed by the Broad Institute (Harvard University and MIT) in Boston, USA.

DIABETESpredict is available in the U.S. and other countries.

Please contact@patiadiabetes.com

Link to the publication: www.nature.com/articles/s41598-019-39145-x

V K Comunicación

Para más información:

Patricia Loredo Sierra

Tfno: 944 01 53 06. Móvil 629 74 90 47

E-mail: patricia@vkcomunicacion.com

MORE ON THIS TOPIC